Thermo Scientific TSQ Endura w/ Transcend II LX-4 & Ultimate Pumps UHPLC

SKU: 3346377

$150,000.00 $115,000.00

1 in stock


Decommissioned by Thermo Fisher, with service records and files. Thermo Fisher Extended warranty available, please enquire.

From forensic toxicology to environmental analysis to pharmaceutical research, a constant in almost every field is the need for greater productivity; to quantify more samples in less time with greater reliability and confidence, and to do it all on ever tighter budgets. The Thermo Scientific Endura Triple Quadruple Mass Spectrometer meets these needs with unsurpassed value. It delivers best-in-class sensitivity run after run and day after day regardless of sample type or matrix, and does so with an ease-of-use that takes the worry out of method development and operation.

System consist of the following items: 

  • Thermo Scientific TSQ Endura Triple Quadrupole Mass Spectrometer
  • (4X) Thermo Dionex UltiMate 3000 RS Pump HPG-3400RS
  • Thermo Dionex Transcend II Valve Interface
  • Thermo Dionex SRD-3600 Solvent Rack with 6 degasser channels
  • (2x) Thermo Scientific PAL: MXY 012-05A Open Autosampler
  • Powervar Security Plus OnLine Uninterruptible Power Supply
  • Peak Scientific  Genius 1022 Nitrogen Generator
  • Sogevac SV40/65 BI FC Rotary Pump
  • Chemyx F100T2 Syringe Pump & Rheodyne MXT715-004 Valve
  • Dell computer with software and monitor

Manufacture Specification 

Thermo Scientific TSQ Endura

  • Positive Electrospray (HESI)- A 2 µL injection of a 500 fg/µL reserpine solution will produce a minimum signal-tonoise ratio of 80,000:1 for the transition of the protonated molecule at m/z 609.3 to the fragment ion at m/z 195.1 when operated in selected-reaction monitoring (SRM) mode with Q1 and Q3 resolution set to 0.4 and  0.7 Da FWHM respectively.
  • Atmospheric Pressure Chemical Ionization (APCI)- A 2 μL loop injection of a 500 fg/μL reserpine solution will produce a minimum signal-to-noise ratio of 25,000:1 for the transition of the protonated molecular ion at m/z 609.3 to the fragment ion at m/z 195.1 when operated in selected reaction monitoring (SRM) mode with Q1 and Q3 resolution both set to 0.7 Da FWHM
  • Negative Electrospray (nESI)- A 2 μL loop injection of a 500 fg/uL chloramphenicol solution will produce a minimum signal-to-noise ratio of 80,000:1 for the transition of the deprotonated molecular ion at m/z 321.0 to the fragment ion at m/z 152.0 when operated in selected reaction monitoring mode (SRM) with Q1 and Q3 resolution set to 0.4 and 0.7 Da FWHM, respectively.
  • Mass Range- m/z 10–3400
  • Resolution- Q1 and Q3 adjustable to 0.4 Da peak width (FWHM) across the entire mass range
  • Scan Rate- 15,000 amu/second at a resolution of 2 FWHM
    500 SRM/second (for any resolution from 0.4 through 2.0 FWHM)
    25msec polarity switching
  • Mass Stability– Mass assignment will be within ±0.05 Da over a 24 hour period. The laboratory room temperature must be maintained between 18–27 °C (65–81 °F). The room temperature may not change by more than  5 °C (9 °F) during this period

 UltiMate 3000 RS Pump HPG-3400RS

Operating Principle

Serial dual-piston

Flow Accuracy

± 0.1% (For BM pumps: ± 0.5%; For NCP-3200RS: < 0.1% RSD at 300 nL/min and 40 MPa)

Flow Precision

< 0.05% RSD or < 0.01 min SD whichever is greater


Typically: < 0.2 MPa or < 1% whichever is greater (For ISO-3100BM pump: Typically: < 0.02 MPa or < 0.1%, whichever is greater)

GLP Features

Full support of Thermo Scientific™ Dionex™ AutoQ instrument qualification, qualification status and system wellness monitoring.
All system parameters are logged in the Chromeleon™ Audit Trail.


USB for PC connection, USB hub with 3 sockets integrated, 15-pin D-sub connector for solvent rack/degasser connection.

Transcend II Valve Interface

  • Minimizes manual sample preparation and facilitates direct sample injection into an LC-MS system—including plasma, urine, food, and other complex matrices
  • Reduces ion suppression through higher specificity
  • Saves time and simplifies complex sample preparation protocols
  • Simplifies method development by enabling the same method to be used for different matrices
  • Accelerates results and quadruples mass spectrometer throughput
  • Enhances productivity by facilitating analysis of more samples per hour
  • Improves efficiency by reducing MS idle time
  • Increases flexibility by allowing up to four different assays to run at the same time

 SRD-3600 Solvent Rack 


Eluent Bottle Capacity (all versions)Nine 1 L bottles,
or four 2.5 L bottles,
or two 5 L bottles and two 1 L bottles
Degassing Channelssix analytical degasser channels
Degassing Channel TubingTeflon AF
Channel Volume670 µL
Maximum Flow Rate/Channel14 mL/min
Optimal Flow Rate/Channel≤3.6 mL/min (for isocratic or gradient formed 50:50 methanol/water blends)
Wetted MaterialsTeflon AF, PEEK, and Tefzel
Status LEDsPower, vacuum pump status, error (vacuum and/or leak)
Communication15-pin D-SUB (through UltiMate 3000 pumps)

 Peak Scientific Genius 1022

Generator Outlets:
  • Gas Type: Nitrogen
  • Gas Flow: 32L/min
  • Outlet Pressure: 100psi
 Sogevac SV40/65 
  • Pumping speed (50/60 Hz): 34.7 / 41.8 cfm
  • Ultimate pressure: < 0.5 mbar
  • Mains connection: 200-240V, 1-ph, 12A, 50/60 Hz
  • Inlet connection: KF-40


Additional information

Weight650 lbs
Dimensions50 × 75 × 65 in
MakeThermo Scientific
ModelTSQ Endura
Item ConditionUsed
IncludesALL cables (power and data)|Computer with Software
Warranty30-Day Warranty, 100% Parts and Labor